Yak Cardiac Transcriptomic and Proteomic Data from Nutritional Supplementation Study

Qinghai-Tibet Plateau data from a study of 12 male Muli yaks subjected to different nutritional regimens over a 60-day period. The dataset contains an integrative transcriptomic-proteomic atlas of yak cardiac tissue, with differential expression analysis yielding 140 DEGs and 254 DEPs. It was authored by Yiqun Chen and last updated in April 2026.

Use Cases

• Analyzing differential gene and protein expression based on 140 DEGs and 254 DEPs identified in the study
• Investigating post-transcriptional regulatory paradigms based on the decoupling between transcriptional and translational landscapes described
• Identifying biomarker candidates for nutritional status based on the coordinated induction of GPX1 and SELENOW
• Studying immune quiescence in cardiac tissue based on the attenuation of stress-responsive immunosurveillance effectors like ULBP13 and GZMB

Strengths

• Integrates transcriptomic and proteomic data from 4,080 cognate gene-protein pairs
• Differential expression analysis provides 140 DEGs and 254 DEPs for comparison
• Includes specific, quantified fold-change values for key proteins like GPX1 and SELENOW

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• Dataset is small (37.5 KB), indicating limited scope or summary-level data

Provenance

Source

figshare, authored by Yiqun Chen

Collection Method

RNA sequencing and data-independent acquisition mass spectrometry of myocardial specimens from a randomized 60-day intervention study

Time Range

Intervention period of 60 days

Freshness

Last updated 2026-04-14 12:39:01; freshness should be verified

Geography

Qinghai-Tibet Plateau