Transcriptional data from purple sea urchin immune cells exposed to UVB-induced genotoxic stress. The dataset likely contains gene expression profiles from single-cell RNA sequencing at six hours post-exposure, identifying phagocytes and vibratile cells as key responders. It was authored by Riss M. Kell and uploaded to figshare in March 2026.
Use Cases
- Identify conserved DDR and innate immune pathway activation based on transcriptional response data.
- Compare cell-type-specific responses to genotoxic stress based on single-cell RNA sequencing results.
- Investigate post-translational modification patterns in signaling pathways based on functional assay results.
- Study the ancestral origins of DDR-immune system crosstalk in basal deuterostomes based on comparative framework.
Strengths
- Data is from a long-lived, cancer-resistant model organism diverged from vertebrates ~550 million years ago.
- Includes results from single-cell RNA sequencing, functional assays, and western blot confirmation.
- Dataset is licensed under CC-BY-4.0 for open reuse.
Limitations
- Row count and column-level documentation are unknown.
- The dataset is 68.4 KB, indicating a limited scope.
- Freshness should be verified as the last update date is March 2026.
Provenance
- Source
- figshare
- Collection Method
- Likely generated from laboratory experiments involving UVB exposure, single-cell RNA sequencing, and functional assays.
- Freshness
- Last updated 2026-03-19 05:18:36