Table 8_Herbst and Twin Block appliances in Class II malocclusion management for children:

A systematic review and meta-analysis comparing Herbst and Twin Block appliances for Class II malocclusion in children, published on figshare in 2026. The work by Franz Tito Coronel-Zubiate synthesizes evidence from seven randomized controlled trials involving 548 participants, with searches conducted up to January 30, 2025. It reports standardized mean differences for skeletal, dental, and soft tissue outcomes.

Use Cases

• Compare treatment efficacy for skeletal parameters based on the meta-analysis of seven RCTs.
• Evaluate dental outcome differences based on reported molar relationship data.
• Assess soft tissue changes based on reported mentolabial angle results.
• Inform clinical decision-making based on synthesized evidence regarding patient-specific factors like adherence and growth stage.

Strengths

• Analysis is based on seven randomized controlled trials, a recognized gold standard for clinical evidence.
• Includes 548 participants, providing a substantive sample size for a meta-analysis in this clinical domain.
• Employs rigorous methodology including Cochrane RoB 2.0 tool and GRADE certainty assessment.
• Clear registration with PROSPERO (CRD420251011083), supporting transparency and reproducibility.

Limitations

• The primary data file is a 675.6 KB DOCX document; the underlying tabular meta-analysis data is not provided as a separate, machine-readable dataset.
• Column-level documentation for any extracted data is absent; field semantics must be inferred from the manuscript.
• Row count for any underlying data tables is unknown, limiting suitability assessment for direct data analysis.

Provenance

Source

Systematic review conducted by author Franz Tito Coronel-Zubiate, sourced from PubMed, Scopus, Web of Science, Cochrane Library, and EMBASE.

Collection Method

Systematic review and random-effects meta-analysis of randomized controlled trials.

Time Range

Literature search conducted until January 30, 2025, with no initial date restriction.

Freshness

Last updated 2026-05-15 07:47:31