Rat Cerebral Cortex Transcriptome and Metabolome Profiles After Subarachnoid Hemorrhage

A 49.3 KB Excel file contains transcriptome and metabolome profiles from the rat cerebral cortex following subarachnoid hemorrhage (SAH). The data, created by Haoran Lu and last updated in April 2026, includes counts of differentially expressed genes and metabolites at 1-day and 7-day post-SAH time points. The description indicates the dataset was generated using whole transcriptome sequencing and untargeted metabolomics assays.

Use Cases

• Identify immune and inflammatory pathway activation based on differentially expressed gene analysis mentioned in the description
• Analyze metabolic pathway alterations such as Arginine and proline metabolism based on the metabolomics results
• Investigate potential links between transcriptomic changes and metabolite levels in a rat model of brain injury
• Explore candidate therapeutic targets for subarachnoid hemorrhage based on the reported aberrant signals

Strengths

• Dataset quantifies 982 differentially expressed genes and 540 differentially expressed metabolites at the 1-day post-SAH time point
• Includes a temporal dimension with data for both 1-day and 7-day post-SAH intervals
• Released under a permissive CC-BY-4.0 license for reuse

Limitations

• Row count and column-level documentation are absent; field semantics must be inferred after download
• The dataset is very small at 49.3 KB, indicating limited scope
• Data is from a specific rat model, which may limit direct translation to human pathology

Provenance

Source

figshare, author Haoran Lu

Collection Method

Whole transcriptome sequencing and untargeted metabolomics assays on rat cerebral cortex tissue

Time Range

Post-subarachnoid hemorrhage time points of 1 day and 7 days

Freshness

Last updated 2026-04-28 14:40:45; freshness should be verified