Nosema ceranae Gene Expression Under Bidens pilosa Treatment in Honey Bees

Transcriptome profiling data from a controlled laboratory experiment on Nosema ceranae-infected honey bees treated with Bidens pilosa extract. The dataset includes gene expression profiles from bee midguts at 5, 10, and 20 days post-infection, generated by author Yi-Hsuan Li and last updated in June 2026. BP treatment was associated with significant downregulation of parasite genes, including components of the V-type ATPase pathway.

Use Cases

• Analyze stage-dependent gene expression changes in Nosema ceranae based on transcriptomic profiles at multiple time points.
• Investigate the molecular impact of phytogenic treatments on parasite metabolic pathways based on Gene Ontology and KEGG analysis results.
• Model the relationship between V-type ATPase pathway suppression and reduced pathogen load based on RNAi-mediated knockdown results.

Strengths

• Data is derived from controlled laboratory cage experiments with 50 bees per replicate and independent repetitions.
• Transcriptomic analysis covers three distinct time points (5, 10, and 20 days post-infection) to capture stage-dependent effects.
• Results are linked to concrete experimental outcomes, including improved survival probability and reduced pathogen load.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The 78.3 KB file size suggests a limited scope of data, likely summary results rather than raw sequencing reads.

Provenance

Source

figshare, author Yi-Hsuan Li.

Collection Method

Transcriptome profiling of N. ceranae from infected honey bee midguts in controlled laboratory cage experiments.

Time Range

Samples collected at 5, 10, and 20 days post-infection.

Freshness

Last updated 2026-06-03 09:29:11; freshness should be verified.