Liubao Tea Multi-Omics Data on Lymphatic Endothelial Cell Metabolism

Multi-omics data from a study investigating the effects of Liubao tea extract on human lymphatic endothelial cell function. The dataset includes results from single-cell transcriptomics, bulk transcriptomics, network pharmacology, and molecular docking analyses, as well as in vitro validation experiments. It was authored by Xiaoxiao Huang and last updated on 2026-05-18.

Use Cases

• Identify potential therapeutic gene targets based on multi-gene integration analysis results.
• Validate molecular docking predictions for Liubao tea components using the provided binding affinity data.
• Analyze the effects of Liubao tea extract on cell survival and migration based on CCK-8 and wound healing experiment results.
• Investigate protein-protein interaction networks involving the PRKCB gene from the PPI analysis.

Strengths

• Includes specific statistical results, such as a fold change of 24.30 for PRKCB expression.
• Integrates multiple analysis methods: single-cell transcriptomics, bulk transcriptomics, network pharmacology, and molecular docking.
• Reports in vitro validation data, including p-values (e.g., p < 0.01) for functional assays.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is very small at 14.8 KB, indicating limited scope.

Provenance

Source

figshare

Collection Method

Combined computational analyses (single-cell/bulk transcriptomics, network pharmacology, molecular docking) with in vitro cell experiments (CCK-8, wound healing, RT-qPCR).

Freshness

Last updated 2026-05-18 05:38:37; freshness should be verified.