FOTP-Based Model Sensitivity for Early Lung Cancer Detection in Plasma cfDNA

Sensitivity metrics for models based on fragmentomic transition probabilities in plasma cell-free DNA. The dataset, authored by Jinwen Ji, was last updated on June 2, 2026. It is a 10.4 KB Excel file containing sensitivity values for consecutive 10-base-pair windows at a fixed 95% specificity threshold.

Use Cases

• Benchmarking the performance of fragmentomic transition probability models based on the described sensitivity metrics.
• Analyzing the relationship between genomic window position and model sensitivity as implied by the 10-bp window data.
• Comparing the diagnostic potential of different cfDNA-based features using the provided sensitivity at a fixed specificity.
• Training or validating secondary models that predict biomarker performance from sequence context.

Strengths

• File size is 10.4 KB, indicating a focused and easily downloadable dataset.
• Specificity is fixed at 95%, providing a consistent benchmark for reported sensitivity values.
• Data is structured in consecutive 10-bp windows, allowing for positional analysis of model performance.

Limitations

• Row count and column definitions are unknown, which complicates suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Collection Method

Likely derived from analysis of plasma cell-free DNA sequencing data, as described in the associated research.

Freshness

Last updated 2026-06-02 07:21:26; freshness should be verified.