Table S3: IHC Staining Quantification in KRAS-G12C Xenograft Tumors

An 18.3 KB Excel file quantifying immunohistochemistry staining in xenograft tumors, created by Xing Wei and last updated on June 1, 2026. The dataset supports research on RAS signaling inhibition and immune checkpoint blockade in KRAS-G12C mutant non-small cell lung cancer. It is shared under a CC-BY-4.0 license on the figshare platform.

Use Cases

• Quantify biomarker expression levels based on IHC staining data mentioned in the description.
• Correlate treatment response with immune cell infiltration in xenograft models based on the described quantification.
• Validate computational models of oncogenic RAS signaling abrogation using the provided experimental measurements.
• Support meta-analyses of combination therapy efficacy for KRAS-mutant cancers using the shared quantification results.

Strengths

• Dataset is small (18.3 KB), facilitating quick download and inspection.
• Clear provenance with a named author (Xing Wei) and a permissive CC-BY-4.0 license.
• Specific focus on a clinically relevant oncogenic mutation (KRAS-G12C) in a defined cancer type (NSCLC).

Limitations

• Row count and column definitions are unknown, limiting suitability assessment.
• Description metadata is limited; actual data quality requires manual inspection after download.
• Data may reflect experimental bias inherent to the specific xenograft model and IHC protocol used.

Provenance

Source

figshare

Collection Method

Likely derived from experimental immunohistochemistry staining and quantification of xenograft tumor samples.

Freshness

Last updated 2026-06-01 07:21:36; freshness should be verified.