Table S3: Placental Cell Type-Specific Sexually Dimorphic Genes

Fold changes for top sexually dimorphic genes in placental cell clusters, identified by single-cell RNA sequencing. The data includes genes upregulated in cells from male and female conceptions, with significance thresholds of |Log2FC|>1 and FDR<0.01. The dataset is associated with an open-access research paper by Tianyanxin Sun.

Use Cases

• Identify sex-biased gene expression patterns in specific placental cell types based on the reported fold changes.
• Validate candidate sexually dimorphic genes for placental function using the provided FDR and expression thresholds.
• Compare gene regulation between male and female conceptions across different cell clusters described in the tables.

Strengths

• Genes are filtered by specific statistical thresholds (|Log2FC|>1, FDR<0.01), indicating a curated list.
• Data is disaggregated by cell cluster, allowing for cell type-specific analysis of sexual dimorphism.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Last update date is unknown; freshness unverified.

Provenance

Source

paperswithcode

Collection Method

Likely derived from single-cell RNA sequencing analysis of placental tissue, as indicated by the description of cell clusters and gene expression.