Meta-Analysis of ICE vs. TEE for Left Atrial Appendage Occlusion in 3,610 Patients

A meta-analysis of twenty clinical studies comparing intracardiac echocardiography (ICE) and transesophageal echocardiography (TEE) for guiding percutaneous left atrial appendage occlusion (LAAO). The study, authored by Zhi-Yuan Zhang and last updated in May 2026, synthesized outcomes from 3,610 atrial fibrillation patients (1,564 in ICE group, 2,046 in TEE group) across four databases up to December 2022. It reports no significant differences in procedural success, time, contrast volume, fluoroscopic time, or complication rates between the two imaging methods.

Use Cases

• Compare procedural efficacy metrics (success rate, time) between ICE and TEE based on the reported risk ratios and weighted mean differences.
• Analyze safety outcomes (complications, adverse events) for different echocardiography guidance methods in LAAO procedures.
• Conduct subgroup analysis on factors like hypertension prevalence, device mechanism, and AF type based on the described subgroup findings.
• Validate or inform clinical guidelines for imaging selection in percutaneous left atrial appendage occlusion procedures.

Strengths

• Analysis is based on a substantial patient cohort of 3,610 individuals from twenty studies.
• Compares multiple specific clinical endpoints: procedural success, total time, contrast volume, fluoroscopic time, complications, and long-term adverse events.
• Includes subgroup analysis for potential confounding factors like hypertension proportion, device type, and AF type.

Limitations

• The dataset is very small (25.8 KB), suggesting it contains summary results rather than patient-level data.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for certain analyses.

Provenance

Source

Zhi-Yuan Zhang via figshare.

Collection Method

Meta-analysis of studies screened from Cochrane Library, Embase, PubMed, and Web of Science.

Time Range

Studies from database inception to 1 December 2022.

Freshness

Last updated 2026-05-15 11:30:36; freshness should be verified.