Neuroprotection Data for Parkinson's Disease Model from Wogonin Study

88.0 MB of TIF files contain experimental data from a study investigating wogonin's neuroprotective effects in a rotenone-induced Parkinson's disease rat model. The dataset likely includes images from histological evaluations and Western blotting analyses. Author Shivani Chib published the data on figshare under a CC-BY-4.0 license.

Use Cases

• Validate computational docking predictions based on the described in-silico molecular dynamics simulations
• Analyze dose-dependent behavioral and biochemical changes based on the described experimental groups and measured markers
• Correlate histological images with quantified protein expression levels based on the described Western blotting and staining
• Study excitatory/inhibitory neurotransmission balance based on the described focus on GABA-A, gephyrin, and parvalbumin

Strengths

• Data is derived from a controlled animal study with six groups and eight rats per group
• Multiple analytical methods are described, including HPLC-ECD, ELISA, Western blotting, and histology
• The dataset is openly available under a CC-BY-4.0 license

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• The dataset consists of TIF files, which may require specific software for analysis

Provenance

Source

figshare

Collection Method

Experimental data from an in vivo study on Wistar rats combined with in silico molecular modeling.

Freshness

Last updated 2026-05-07 07:36:02