Mouse Plasma Proteomics from Spaceflight Myostatin Study

NASA research on physiological changes in mice during a 33-day spaceflight mission to the International Space Station. The dataset includes plasma proteomics data from wild-type and genetically modified mice, used to study the effects of targeting myostatin/activin A signaling on muscle and bone mass. Data was last updated on March 13, 2026.

Use Cases

• Identify plasma protein biomarkers for muscle and bone loss based on proteomic profiles.
• Compare signaling pathway alterations between microgravity and ground control groups.
• Evaluate the therapeutic effect of myostatin/activin A inhibition on physiological metrics.

Strengths

• Data originates from a controlled spaceflight experiment conducted by NASA.
• Includes results from both genetic (Mstn -/-) and pharmacological (soluble ACVR2B receptor) intervention approaches.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data is provided in a BIN file format, which may require specialized tools for access.

Provenance

Source

National Aeronautics and Space Administration

Collection Method

Experimental data from mice sent to the International Space Station, analyzed using plasma proteomics.

Freshness

Last updated 2026-03-13 19:40:41.460313; freshness should be verified.