TAT.ARC Protein Study: Regional Ischemic Lesion Volumes from MRI After MCA Occlusion

Stefan Donath's research dataset contains MRI-derived volumetric measurements of ischemic stroke lesions in a rodent model. The data likely includes total and regional lesion volumes calculated from T2-weighted images after 60 minutes of middle cerebral artery occlusion, analyzed at 24-hour and 72-hour time points using Analyze 5.0 and ImageJ software. The dataset was sourced from the paperswithcode platform and is available under an Open Access (green) license.

Use Cases

• Validate automated lesion segmentation algorithms based on the described threshold-based ROI method.
• Study the spatiotemporal progression of ischemic damage based on regional volume measurements from medial to lateral brain slices.
• Correlate biochemical assay results from brain tissue with corresponding MRI-derived lesion volumes mentioned in the description.

Strengths

• Data is derived from a controlled experimental model with a defined 60-minute MCA occlusion protocol.
• Volumetric analysis was performed using established software tools (Analyze 5.0 and ImageJ) as described.

Limitations

• Row count and dataset size are unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Last update date is unknown; freshness unverified.

Provenance

Source

Stefan Donath via paperswithcode

Collection Method

Experimental data from a rodent stroke model, with MRI images processed via Analyze 5.0 and ImageJ software.