Longitudinal Cortical Calcium Imaging in Adult Mice Following Vision Loss

Longitudinal mesoscopic calcium imaging data from the dorsal cortex of spontaneously behaving adult mice before and after bilateral enucleation. The dataset, 4.6 GB in size, was published by Ismaël Djerourou on figshare in 2026 under a CC-BY-4.0 license. It captures activity changes over two sequential, overlapping windows spanning from day 1 to week 10 post-injury.

Use Cases

• Modeling cortical state plasticity over time based on longitudinal calcium imaging data.
• Analyzing behavior-dependent changes in network structure based on locomotion and quiescence transitions.
• Investigating spatial dissociations in plasticity between visual and retrosplenial cortices.
• Identifying temporal windows of reduced and heightened excitability following sensory loss.

Strengths

• Longitudinal design capturing data before and after intervention over a period of up to 10 weeks.
• Large dataset size of 4.6 GB, suggesting substantial raw data volume.
• Openly licensed under CC-BY-4.0, permitting reuse and redistribution.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data is specific to a mouse model of bilateral enucleation, limiting direct human applicability.

Provenance

Source

Ismaël Djerourou via figshare.

Collection Method

Longitudinal mesoscopic calcium imaging performed on adult mice.

Time Range

Data captured before and after bilateral enucleation, covering two plasticity windows from day 1 to week 10.

Freshness

Last updated 2026-04-28 01:30:13; freshness should be verified.

Geography

Laboratory study, likely null for geographic coverage.