Efgartigimod Efficacy in Autoimmune Encephalitis: Clinical and Immunological Data

A retrospective cohort study of 15 autoimmune encephalitis patients treated with efgartigimod, authored by Jin Qin and last updated in May 2026. It includes modified Rankin Scale (mRS) and Clinical Assessment Scale for Autoimmune Encephalitis (CASE) scores, immunological parameters, and routine laboratory data. The dataset is shared under a CC-BY-4.0 license on figshare.

Use Cases

• Analyze clinical improvement based on mRS and CASE score changes mentioned in the description
• Investigate the relationship between serum IgG reduction and clinical response based on immunological parameters
• Assess treatment safety profiles based on adverse event and routine laboratory data
• Compare treatment efficacy across patient subgroups based on neuronal surface autoantibody status

Strengths

• Includes clinical outcome data from 15 patients with autoimmune encephalitis
• Reports statistically significant improvements in mRS and CASE scores (p < .001)
• Contains longitudinal data on serum IgG levels before and after treatment
• Explicitly reports no serious adverse events were observed

Limitations

• Small sample size of 15 patients limits statistical power and generalizability
• Retrospective study design cannot establish causal relationships
• Column-level documentation is absent; field semantics must be inferred after download

Provenance

Source

figshare

Collection Method

Retrospective analysis of patient medical records.

Freshness

Last updated 2026-05-20 09:19:59