Candida Bloodstream Infections and Endocarditis in a Pediatric Hospital, 2007-2016

Only two cases of Candida infective endocarditis were identified among 221 pediatric patients with positive Candida blood or catheter cultures over a nine-year period. Ahu Kara conducted this retrospective study at a tertiary hospital, analyzing 256 infection attacks from January 2007 to January 2016. The most common Candida species was Candida parapsilosis, isolated in 61.3% of attacks.

Use Cases

• Estimating the incidence of Candida infective endocarditis based on patient cohort data from a tertiary hospital.
• Analyzing the distribution of Candida species (e.g., Candida parapsilosis, Candida albicans) in pediatric bloodstream infections.
• Investigating associations between comorbidities (e.g., neurological diseases, hemato-oncological diseases) and Candida infection outcomes.
• Evaluating the application of modified Duke criteria for defining infective endocarditis in a pediatric clinical setting.

Strengths

• Includes data from 221 patients and 256 infection attacks, providing a specific cohort size.
• Covers a nine-year study period from January 2007 to January 2016, offering longitudinal insight.
• Reports specific incidence figures, such as Candida endocarditis in 0.9% of patients and the prevalence of Candida parapsilosis in 61.3% of attacks.

Limitations

• Row count and column-level documentation are absent; field semantics must be inferred after download.
• Data may reflect temporal and institutional bias inherent to a single tertiary hospital study.
• Last update date is unknown; freshness unverified.

Provenance

Source

Ahu Kara via paperswithcode

Collection Method

Retrospective study of patients with positive Candida blood or catheter cultures at a tertiary hospital.

Time Range

January 2007 to January 2016