Mouse Model Data on IL-17A and Neutrophils in Streptococcus Suis Infection

Mouse infection data from a study investigating an ultra-virulent Streptococcus suis serotype 5 strain SC2022MYS167. The dataset likely contains measurements of bacterial loads, cytokine levels, and neutrophil counts in peripheral blood and organs. Author han zheng published the data on figshare in May 2026.

Use Cases

• Analyze the relationship between bacterial load and cytokine levels based on measurements in peripheral blood and organs.
• Investigate the role of IL-17A-producing neutrophils in lethal infection based on cytokine and cell count data.
• Model the dose-dependent effect of neutrophil depletion on infection outcomes based on antibody treatment data.
• Compare inflammatory responses across lung, liver, and spleen tissues based on pro-inflammatory cytokine measurements.

Strengths

• Data is associated with a specific, named clinical strain SC2022MYS167.
• Includes results from intervention experiments (IL-17A blocking and neutrophil depletion).
• Published under a CC-BY-4.0 license for open reuse.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data may reflect bias inherent to a single clinical strain and mouse model.

Provenance

Source

figshare

Collection Method

Likely generated from laboratory experiments on mice infected with Streptococcus suis.

Freshness

Last updated 2026-05-08 08:16:11; freshness should be verified.