Impact of Hydration Volume on Kidney Function in Biliary Tract Cancer Patients

239 patients with biliary tract cancer receiving low-dose cisplatin therapy were analyzed in a multicentre retrospective study. The research, authored by Hiroyuki Watanabe and last updated in May 2026, compared acute kidney injury incidence between low-volume and high-volume hydration protocols. Post-adjustment results showed a 4.7% AKI rate with low-volume hydration versus 10.1% with high-volume, supporting non-inferiority.

Use Cases

• Assessing non-inferiority of treatment protocols based on acute kidney injury incidence.
• Analyzing patient outcomes based on hydration volume and cisplatin dosage mentioned in the description.
• Applying propensity score weighting techniques to adjust for confounders in retrospective clinical data.

Strengths

• Data covers 239 patients from a multicentre study, providing a multi-source perspective.
• Primary endpoint (acute kidney injury incidence) and key metrics like serum creatinine are explicitly defined.
• Analysis employed propensity score weighting to adjust for confounders.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 33.0 KB, indicating limited scope.

Provenance

Source

figshare, author Hiroyuki Watanabe.

Collection Method

Multicentre retrospective cohort study.

Freshness

Last updated 2026-05-20 13:20:02; freshness should be verified.