ZNF295-AS1 and miR-96-5p Expression in Lung Squamous Cell Carcinoma

116 patients with lung squamous cell carcinoma provided tissue samples for this study. Yan Huang authored this research dataset, which includes expression levels of the long non-coding RNA ZNF295-AS1 and microRNA miR-96-5p. The data suggests ZNF295-AS1 acts as a protective factor by regulating miR-96-5p to inhibit cancer cell proliferation, migration, and invasion.

Use Cases

• Identifying prognostic biomarkers for lung squamous cell carcinoma based on ZNF295-AS1 expression levels.
• Studying the regulatory relationship between long non-coding RNAs and microRNAs based on the ZNF295-AS1 and miR-96-5p interaction.
• Modeling cancer cell invasiveness based on molecular expression data from clinical tissue samples.

Strengths

• Includes data from 116 patient tissue samples, providing a clinical cohort.
• Compares cancerous tissue to adjacent normal tissue from the same patients.
• Links molecular expression data (ZNF295-AS1, miR-96-5p) to functional assays for proliferation, migration, and invasion.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset size is 1.0 MB, indicating a relatively small scale of data.

Provenance

Source

figshare

Collection Method

Tissue samples were obtained during surgery from 116 patients with lung squamous cell carcinoma, with expression levels assessed via RT-qPCR.

Freshness

Last updated 2026-05-26 05:13:11; freshness should be verified.