ESRRA Regulation of Acute Kidney Injury via Lipophagy-Ferroptosis Axis

Yuanting Yang's research dataset, last updated May 2026, investigates the role of the nuclear receptor ESRRA in acute kidney injury. The 33.8 MB dataset contains supporting documents for a study that used single-cell transcriptomics and mouse models to identify ESRRA as a protective factor modulating the RAB7-dependent lipophagy-ferroptosis axis. The data is available under a CC-BY-4.0 license.

Use Cases

• Analyzing transcriptional regulation in acute kidney injury based on the described ChIP-seq and JASPAR database analyses.
• Studying the relationship between lipophagy and ferroptosis in disease models based on the described mouse and cell line experiments.
• Investigating the AKT-MTOR signaling pathway's role in renal protection based on the mechanistic findings described.

Strengths

• Dataset is 33.8 MB in size, providing a specific scale for download.
• Includes data from integrated analyses such as single-cell transcriptomics and ChIP-seq, as described.
• Released under a permissive CC-BY-4.0 license for reuse.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data files are in PDF and DOCX formats, which are not inherently machine-readable for analysis.

Provenance

Source

figshare

Collection Method

Likely contains experimental data from mouse models, single-cell transcriptomic analysis, and chromatin immunoprecipitation sequencing (ChIP-seq).

Time Range

null

Freshness

Last updated 2026-05-06 06:39:57; freshness should be verified.

Geography

null