Mouse Immunogenicity Data for Recombinant ASFV-PRV Vaccine

Data from 2026 evaluates the safety and immune response of a recombinant pseudorabies virus expressing African swine fever virus proteins in a murine model. The dataset contains results from immunogenicity and challenge experiments, including antibody levels and viral load measurements. It was created by Shuai Zhang to support vaccine development for African swine fever.

Use Cases

• Analyze anti-p30 and anti-CD2v antibody levels to correlate with vaccine immunogenicity.
• Compare viral copy numbers in tissues from PRV-challenged mice to assess vaccine protection efficacy.
• Evaluate Th1/Th2 immune response balance from cellular immunity data to characterize vaccine-induced immunity.

Strengths

• Data originates from a 2026 study, providing recent experimental results.
• Includes specific metrics for vaccine evaluation, such as antibody titers and viral copy numbers.
• Released under a CC BY 4.0 license, permitting open sharing and adaptation.

Limitations

• The dataset is 125.4 KB, indicating a limited scope likely containing summary or key result tables.
• Data is restricted to a murine model, limiting direct extrapolation to swine or other species.
• Sample size and specific row/column counts are not provided, obscuring the dataset's granularity.

Provenance

Source

Shuai Zhang via figshare.

Collection Method

Generated from laboratory experiments using CRISPR/Cas9 and homologous recombination to construct and test a recombinant virus.

Time Range

2026.

Freshness

Last updated in March 2026.

Geography

Study context relates to China, but specific experimental location is unknown.