Plasma Metabolome and Clinical Features of Coeliac Disease Patients in Northwest China

Plasma metabolomic profiles and dietary intake data for 15 patients with coeliac disease, 15 healthy volunteers, and 30 patients with inflammatory bowel disease in Northwest China. The dataset was generated using a pseudo-targeted metabolomics approach via UHPLC-QTRAP-MS analysis and was last updated on 2026-05-17. Author Wang Zhang released the data under a CC-BY-4.0 license.

Use Cases

• Identify metabolic biomarkers for coeliac disease based on altered pathways like the pentose phosphate pathway and citric acid cycle.
• Compare host metabolic profiles between coeliac disease and inflammatory bowel disease patients.
• Investigate relationships between dietary nutrient intake and plasma metabolite levels.
• Analyze the role of gut microbiota-derived metabolites, such as aromatic amino acid metabolites, in coeliac disease.

Strengths

• Includes data from three distinct cohorts: 15 CeD patients, 15 healthy controls, and 30 IBD patients.
• Metabolomics data was adjusted for energy and 17 specific nutrient covariates from food frequency questionnaires.
• Analysis performed using a specific, documented technique: pseudo-targeted metabolomics via UHPLC-QTRAP-MS.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The cohort size of 15 CeD patients is relatively small, limiting statistical power.

Provenance

Source

figshare

Collection Method

Plasma samples collected from patients and volunteers; metabolomic analysis performed via UHPLC-QTRAP-MS.

Freshness

Last updated 2026-05-17 03:31:36; freshness should be verified.

Geography

Northwest China