β-Thujaplicin Renal Tubular Iron Mobilization in Diabetic Kidney Disease Mouse Model

Fengning Yang published a 165.9 MB dataset on figshare in 2026. The data consists of TIF files from a study investigating iron metabolism in diabetic kidney disease using a mouse model. The research employed transcriptome analysis and cell culture experiments to explore the therapeutic effects of β-Thujaplicin on renal fibrosis.

Use Cases

• Analyze renal iron deposition patterns based on the described mouse model of diabetic kidney disease.
• Study the correlation between tubular iron levels and fibrotic markers as mentioned in the research description.
• Investigate the effects of β-Thujaplicin on TGF-β signaling pathway inhibition described in the transcriptome analysis.
• Validate imaging-based findings on iron mobilization and fibrosis attenuation referenced in the study.

Strengths

• Dataset is 165.9 MB in size, indicating a medium-scale collection of image files.
• The research methodology is described in detail, including the use of a unilateral nephrectomy and streptozotocin-induced mouse model and HK-2 cell experiments.
• Data is shared under a permissive CC-BY-4.0 license.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset consists solely of TIF files, which may require specialized software for analysis.

Provenance

Source

figshare

Collection Method

Data likely generated from laboratory experiments involving mouse models and cell culture, as described in the associated research.

Freshness

Last updated 2026-04-30 05:42:13; freshness should be verified.