Histological images of TNFR2-MF-KO (Tumor Necrosis Factor Receptor 2 Myofibroblast Knockout) tissue samples stained with Picrosirius red. Created by Eirini Kefalogianni as part of an AHA 2020 Career Development Award project, the collection was last updated in March 2026. The data focuses on visualizing collagen deposition and fibrosis in specific genetic knockout models.
Use Cases
- Automated quantification of collagen area fraction in Picrosirius red stained images
- Training deep learning models for fibrosis detection in TNFR2-MF-KO tissue sections
- Comparative morphological analysis of myofibroblast-specific TNFR2 knockout effects
Strengths
- Specific genetic model (TNFR2-MF-KO) for targeted fibrosis research
- Standardized Picrosirius red staining for collagen visualization
- Produced under an American Heart Association (AHA) Career Development Award
Limitations
- Unknown sample size and image dimensions
- Lack of explicit metadata regarding experimental controls or animal age
- No information provided regarding the magnification levels used during imaging
Provenance
- Source
- Eirini Kefalogianni, AHA 2020 CDA
- Collection Method
- Histological staining and microscopy imaging
- Freshness
- Last updated March 4, 2026.