EEG and Clinical Features of Neurological Episodes in Amyloidosis Patients Post-Transplant

A retrospective analysis of 155 patients with hereditary ATTRv amyloidosis who underwent liver transplantation and had at least one EEG. The study, authored by Gonçal Videira, was posted on figshare in 2026 and reports that 76.8% of patients experienced transient focal neurological episodes (TFNEs). It correlates EEG findings like focal slow activity with TFNE occurrence, cognitive impairment, and reduced survival.

Use Cases

• Predicting neurological episode risk based on EEG findings like focal slow activity.
• Analyzing the association between specific TFNE clinical subtypes (e.g., seizure-like, migraine-like) and patient outcomes.
• Modeling the correlation between EEG patterns (posterior dominant rhythm slowing) and cognitive impairment domains.
• Studying the efficacy of anti-seizure medication regimens in a post-liver transplant amyloidosis cohort.

Strengths

• Includes data from 155 patients, providing a defined cohort size.
• Reports specific statistical findings, such as a 40.0% detection rate of focal slow EEG activity and odds ratios (OR=2.91) for associations.
• Clinical features are categorized into five distinct TFNE subtypes with reported prevalence percentages (e.g., 37.0% seizure-like).

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small (30.1 KB), indicating limited scope, likely containing summary statistics or a manuscript rather than raw patient records.

Provenance

Source

figshare, author Gonçal Videira.

Collection Method

Retrospective analysis of patient records and electroencephalograms (EEGs).

Freshness

Last updated 2026-06-04 16:33:18; freshness should be verified.