TRIM-NHL and Biomolecular Condensates in Cardiac Aging

A dataset from a project examining mitochondria-associated TRIM-NHL ubiquitin E3 ligases in aged SAMP8 mouse hearts. The data was generated by Dhanendra Tomar using proximity labeling and omics techniques to explore links between RNA granules, mitochondrial function, and cardiac aging. It was last updated on June 1, 2026.

Use Cases

• Identify TRIM-NHL-bound RNA granules based on proximity labeling data.
• Analyze mitochondrial-anchored RNA interactions in aged cardiac tissue.
• Investigate the role of ubiquitin E3 ligases in cardiac proteostasis during aging.
• Explore the relationship between biomolecular condensates and mitochondrial function in a disease model.

Strengths

• Focuses on a previously unexplored link among RNA granules, mitochondrial function, and cardiac aging.
• Uses proximity labeling and omics techniques, suggesting a multi-modal experimental approach.
• Released under the permissive CC-BY-4.0 license for open use.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The description is specific to the research project but lacks concrete details on the final data structure.

Provenance

Source

Dhanendra Tomar via figshare

Collection Method

Proximity labeling and omics analysis of aged SAMP8 mouse hearts.

Freshness

Last updated 2026-06-01 22:08:25; freshness should be verified.