SelenoCanns: Novel Seleno-Cannabinoid Compounds with CB1 Receptor Binding Affinity

A collection of novel selenosulfonyl homologated compounds, termed SelenoCanns, bearing cannabinoid receptor-1 recognition motifs. The dataset, authored by Malliga R. Iyer, was last updated on April 28, 2026. It likely contains structural data for compounds synthesized via a programmable platform using Na2SeSO3 as a selenium source.

Use Cases

• Structure-activity relationship (SAR) modeling based on novel seleno-cannabinoid chemotypes.
• Virtual screening for drug discovery based on compounds with nanomolar to sub-nanomolar CB1 receptor binding affinity.
• Design of covalent-drug conjugates or fluorescent probes based on the described seleno-homologation platform.

Strengths

• Compounds were synthesized via a described, expeditious, and sustainable platform using a benign selenium source.
• Many compounds in the collection showed nanomolar to sub-nanomolar binding affinity for the CB1 receptor.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 8.0 KB, indicating limited scope.

Provenance

Source

figshare

Collection Method

Target-oriented synthesis via a programmable chemical synthesis platform.

Freshness

Last updated 2026-04-28 08:05:19; freshness should be verified.