Uric Acid and CKD Risk in Dyslipidemic Patients, 1,269 Individuals

An observational study of 1,269 dyslipidemic individuals in Greece followed for a median of 6 years. The dataset, associated with a research paper by Fotios Barkas, examines the correlation between baseline uric acid levels and incident chronic kidney disease, adjusting for factors like age, gender, diabetes, and cardiovascular disease. 11.9% of the eligible cohort developed CKD during follow-up.

Use Cases

• Predicting incident chronic kidney disease based on baseline uric acid levels and patient demographics.
• Analyzing the hazard ratio of various risk factors like age, gender, and diabetes for CKD development.
• Studying the association between low-density lipoprotein cholesterol reduction and CKD risk in treated patients.
• Investigating the differential CKD risk across defined uric acid quartiles (e.g., <4 mg/dL vs. >6 mg/dL).

Strengths

• Includes 1,269 patient records with a median follow-up period of 6 years.
• Multivariate analysis results are provided, including hazard ratios and confidence intervals for multiple variables.
• Specific exclusion criteria (baseline eGFR <60, gout, UA-lowering drugs) are documented, clarifying the study cohort.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count for the final analytical dataset (1,095 eligible individuals) is known, but the full variable set is not described.
• Last update date is unknown; freshness unverified.

Provenance

Source

Fotios Barkas (via paperswithcode)

Collection Method

Observational study conducted in a lipid clinic in Greece.

Time Range

Follow-up period median 6 years (IQR 4-10 years).

Geography

Greece