FOXA1 Chromatin Occupancy in TRIM28-Overexpressing Prostate Cancer Cells

Chromatin immunoprecipitation sequencing data investigates the effect of TRIM28 overexpression on FOXA1 chromatin occupancy in prostate cancer cells. The dataset is 566.4 MB in size and was authored by Xiangpeng Zhan, last updated on May 17, 2026. It is shared under a CC-BY-4.0 license on the figshare platform.

Use Cases

• Analyze changes in FOXA1 binding sites based on TRIM28 overexpression levels mentioned in the description
• Identify genomic regions where chromatin occupancy is altered in different prostate cancer cell lines
• Validate hypotheses about TRIM28's role as a transcriptional co-regulator in cancer pathways
• Integrate ChIP-seq findings with other omics data for systems biology studies of prostate cancer

Strengths

• Dataset size is 566.4 MB, indicating substantial sequencing depth
• Explicitly focuses on the interaction between two key cancer-related proteins, FOXA1 and TRIM28
• Shared under a permissive CC-BY-4.0 license for broad reuse

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Description metadata is limited; actual data quality requires manual inspection after download

Provenance

Source

figshare

Collection Method

Chromatin immunoprecipitation sequencing (ChIP-seq)

Freshness

Last updated 2026-05-17 14:46:06; freshness should be verified