Vascular Territory and Brain Templates in MNI Space from 16 Subjects

Sixteen subjects (mean age 69.6) were recruited to generate a high-resolution multimodal brain template. The dataset includes T1, T2, and 3D-FLAIR templates and a vascular territory map, all registered to MNI space, created by researchers at Harvard University. The vascular map outlines ACA, MCA, and PCA territories and was manually assessed and corrected.

Use Cases

• Spatial normalization of brain scans based on the provided MNI-registered templates
• Analysis of white matter hyperintensities in relation to vascular territories based on the FLAIR template
• Segmentation of cerebral vascular territories for stroke research based on the provided territory map
• Creation of study-specific brain atlases using the high-resolution T1, T2, and FLAIR templates

Strengths

• Includes multimodal imaging data (T1, T2, 3D-FLAIR) from a 3T Siemens scanner
• Templates are derived from 16 subjects and manually assessed for gross pathology
• Vascular territory map contains anatomically validated ACA, MCA, and PCA territories

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• The cohort is specific (12 patients with cerebral amyloid angiopathy and 4 controls), which may limit generalizability

Provenance

Source

Harvard University, associated with a publication in Frontiers in Neurology.

Collection Method

MRI scans from 16 subjects were processed using Advanced Normalization Tools (ANTs) to create templates and a vascular map.