VCF: Complement System Polymorphisms in 154 Spanish COVID-19 Patients

Spanish patients from the first wave of the COVID-19 pandemic provide the geographic scope for this dataset. It contains VCF files documenting complement system polymorphisms for a cohort of 154 individuals. The data was authored by Alberto Lopez Lera and is shared under a CC-BY-4.0 license.

Use Cases

• Assess genetic association between complement system variants and COVID-19 severity based on the described patient cohort.
• Investigate population-specific allele frequencies of complement system polymorphisms within the Spanish population mentioned in the description.
• Perform secondary analysis on genetic data from the early pandemic period referenced in the description.

Strengths

• Data is focused on a specific, clinically relevant genetic system (complement system) for a defined disease (COVID-19).
• The cohort size is explicitly stated as 154 patients.
• The dataset is shared under a permissive CC-BY-4.0 license.

Limitations

• The dataset is very small at 14.4 KB, indicating limited scope.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

Alberto Lopez Lera via figshare.

Collection Method

Likely gathered from genetic sequencing of patient samples, though the specific method is not detailed.

Time Range

First wave of the COVID-19 pandemic.

Freshness

Last updated 2026-05-20 10:06:04; freshness should be verified.

Geography

Spain.