Virulence factors and antibiotic resistance of Helicobacter pylori isolated from raw milk

103 out of 520 raw milk samples and 77 out of 400 traditional dairy product samples from Iran were found to be contaminated with Helicobacter pylori. The dataset, created by Soolmaz Mousavi, includes analysis of virulence factors (vacA, cagA, iceA, oipA) and antimicrobial resistance properties for the isolated strains. Antimicrobial susceptibility testing was performed using the disk diffusion method.

Use Cases

• Analyze the prevalence of specific virulence factors (vacA, cagA, iceA, oipA) in H. pylori strains from food sources.
• Study antimicrobial resistance patterns in H. pylori based on disk diffusion test results for antibiotics like ampicillin and tetracycline.
• Compare contamination rates of H. pylori between different sample types such as ovine milk and traditional cheese.
• Investigate potential links between foodborne H. pylori strains and human infection severity.

Strengths

• Sample sizes are provided: 520 raw milk and 400 dairy product samples.
• Prevalence statistics are detailed for contamination (19.8% in milk) and for four virulence factors (e.g., 76.6% for cagA).
• Antibiotic resistance levels are quantified for multiple drugs (e.g., 84.4% resistance to ampicillin).

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data may reflect geographic bias inherent to the single-country (Iran) sampling.

Provenance

Source

paperswithcode

Collection Method

Samples were cultured and tested; H. pylori-positive isolates were analyzed for virulence factors and antimicrobial susceptibility via disk diffusion.

Geography

Iran