Virtual Histological Staining of Lung Micro-CT Volumes

VISTACT provides phase-contrast micro-computed tomography volumes of human lung tissue paired with serial histological sections stained with Elastin-van-Gieson. The dataset, created by cristinaperez9, also includes PCμCT data from mouse heart-lung tissue with H&E stains and was last updated in March 2026.

Use Cases

• Train image-to-image translation models to generate virtual EvG histological stains from PCμCT volumes of human lung tissue.
• Develop and validate algorithms for 3D pathology reconstruction by aligning serial histological sections with their corresponding micro-CT volumes.
• Analyze structural features in mouse heart-lung tissue PCμCT data to correlate with H&E stained ground truth sections.
• Benchmark machine learning models for non-destructive, label-free tissue analysis using the paired micro-CT and gold-standard histology data.

Strengths

• Includes gold-standard Elastin-van-Gieson stained histology for pulmonary hypertension pathology.
• Provides paired 3D micro-CT volumes and 2D histological sections for multimodal analysis.
• Dataset contains samples from both human lung and mouse heart-lung tissue.

Limitations

• Specific sample counts, volume dimensions, and dataset size are not provided in the description.
• Geographic origin and demographic details of the human tissue samples are unknown.
• License terms are not specified, which may restrict commercial use or redistribution.

Provenance

Source

huggingface.co/datasets/cristinaperez9/VISTACT

Collection Method

Phase-contrast micro-computed tomography imaging paired with physical serial sectioning and histological staining.

Time Range

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Freshness

Last updated March 2026.

Geography

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