YoDA-C: Youth Depression Trial Data with CBT and Fluoxetine Outcomes

De-identified demographic, clinical, and outcome data from the Youth Depression Alleviation - Combined Treatment randomised controlled trial. The dataset includes data from young people aged 15-25 with moderate to severe major depressive disorder, collected at baseline and weeks 4, 8, and 12 during a 12-week treatment period. It was published by MACH HeSANDA and is available for secondary research and meta-analysis.

Use Cases

• Compare treatment efficacy based on depression severity scores (Montgomery-Åsberg Depression Rating Scale) mentioned in the description
• Analyze treatment adherence and its relationship to clinical outcomes based on adherence data mentioned in the description
• Study comorbid anxiety and suicidal behaviors in a youth depression cohort based on the described assessment variables
• Model longitudinal depression symptom trajectories based on data collected at multiple time points mentioned in the description

Strengths

• Data originates from a randomised, double-blind, placebo-controlled trial, a gold-standard study design
• Includes longitudinal measurements collected at four specific time points over a 12-week period
• Focuses on a specific demographic of young people aged 15-25 years with moderate to severe major depressive disorder

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Data may reflect geographic bias inherent to its collection in metropolitan Melbourne, Australia

Provenance

Source

MACH HeSANDA via figshare

Collection Method

Collected as part of the Youth Depression Alleviation - Combined Treatment (YoDA-C) randomised controlled trial

Time Range

Data collection occurred at baseline and weeks 4, 8, and 12 of the trial

Freshness

Last updated 2026-04-28 23:29:09; freshness should be verified

Geography

Metropolitan Melbourne, Australia