Ampicillin Trihydrate Assay Data via Spectrophotometric Methods

A research dataset describes spectrophotometric methods for determining Ampicillin Trihydrate concentration in pharmaceutical formulations. The methods were validated per ICH guidelines and show linear calibration in the 5-25 μg/ml range with reported r² values of 0.999. The dataset was authored by Digambar MA and shared via the paperswithcode platform.

Use Cases

• Validate spectrophotometric assay methods based on the described zero-order derivative technique.
• Compare analytical performance between zero-order and area-under-the-curve methods based on the reported validation metrics.
• Develop calibration models for drug concentration based on the linear range and wavelengths mentioned in the description.

Strengths

• Methods were validated per ICH guidelines, suggesting adherence to a recognized standard.
• Calibration graphs were linear in the 5-25 μg/ml concentration range.
• Reported correlation coefficients (r²=0.999) for both methods indicate strong linearity.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Last update date is unknown; freshness unverified.

Provenance

Source

paperswithcode

Collection Method

Developed spectrophotometric methods for drug assay.