Crystal Structure of Saquinavir Bound to Multi-Drug Resistant HIV-1 Protease

Crystal structure data of the inhibitor saquinavir (SQV) in complex with a multi-drug resistant HIV-1 protease variant (L63P/V82T/I84V). The dataset is associated with a paper by author M. Prabu-Jeyabalan and is hosted on the Papers with Code platform. The specific data format, size, and number of records are not detailed in the available metadata.

Use Cases

• Analyzing protein-ligand interactions for a drug-resistant HIV protease variant (inferred from domain, verify after download)
• Training or validating molecular docking or binding affinity prediction models (inferred from domain, verify after download)
• Studying structural basis of multi-drug resistance in HIV-1 (inferred from domain, verify after download)

Strengths

• Published on the Papers with Code platform.
• Associated with a specific scientific paper and author.

Limitations

• Metadata is minimal; actual content requires verification after download.
• Column-level documentation is absent; field semantics must be inferred after download.
• License is listed as 'closed', which may restrict usage.

Provenance

Source

M. Prabu-Jeyabalan