A third QueE enzyme structure from Escherichia coli establishes the middle range of structural variation observed in homologs. The dataset compares and contrasts the structural architecture of three 7-carboxy-7-deazaguanine synthases. It was contributed by Tsehai A.J. Grell of the Massachusetts Institute of Technology.
Use Cases
- Compare structural variations in AdoMet radical enzymes based on the described TIM barrel fold.
- Hypothesize about enzyme-reductant interactions based on the described structural differences between three homologs.
- Analyze the relationship between protein structure and catalytic activity based on the described focus on enzyme tailoring.
Strengths
- Focuses on a specific, high-resolution structural biology technique: X-ray crystallography.
- Provides a comparative analysis of three homologs, establishing a spectrum of structural variation.
Limitations
- Row count and dataset scale are unknown, which may limit suitability assessment.
- Column-level documentation is absent; field semantics must be inferred after download.
- Last update date is unknown; freshness unverified.
Provenance
- Source
- Tsehai A.J. Grell, Massachusetts Institute of Technology
- Collection Method
- X-ray crystallography.