Anthrax Lethal Factor Crystal Structure from Nature Publication

Nature published the crystal structure of the anthrax lethal factor, a protein critical to anthrax pathogenesis. The dataset comprises the scientific paper describing this structure, released online by Nature in 2001. The research was conducted by Panniter, A. et al. and is associated with the organization SCIOPS.

Use Cases

• Analyze the atomic coordinates and protein fold described in the paper for structural homology modeling.
• Study the active site and binding pockets of the lethal factor for structure-based inhibitor design.
• Use the published structural data to validate computational protein structure prediction models.
• Reference the crystallographic resolution and methodology for comparative analysis with other toxin structures.

Strengths

• Primary source data from a peer-reviewed Nature publication in 2001.
• Describes a specific, high-impact protein structure critical to a major pathogen.

Limitations

• The dataset is a single scientific paper, not a large-scale collection of structural data.
• Structural data is from 2001 and may not reflect the most recent experimental or computational refinements.

Provenance

Source

Nature journal online special release.

Collection Method

X-ray crystallography as described in the primary research paper.

Time Range

Publication year 2001.