Markus Hassler from the European Molecular Biology Laboratory presents a dataset containing the crystal structure of the C. thermophilum condensin Smc2 ATPase head. The data was used to reconstruct the sequence of events during the condensin ATPase cycle at near-atomic resolution. The dataset is associated with an Open Access (green) license.
Use Cases
- Modeling protein conformational changes based on the described ATP-induced switch in the Smc4 head domain.
- Simulating large-scale transitions in condensin architecture based on the described ring-opening mechanism.
- Analyzing protein-protein interactions based on the described engagement between Smc2 and Smc4 heads.
- Studying nucleotide binding dynamics based on the described sequence of events at the ATPase active sites.
Strengths
- Data is derived from near-atomic resolution reconstruction of a protein complex.
- Dataset is associated with a specific, peer-reviewed research finding published on paperswithcode.
- The dataset is licensed as Open Access (green), facilitating reuse.
Limitations
- Column-level documentation is absent; field semantics must be inferred after download.
- Row count is unknown, which may limit suitability assessment.
- Last update date is unknown; freshness unverified.
Provenance
- Source
- European Molecular Biology Laboratory (Author: Markus Hassler)
- Collection Method
- Crystallography and structural analysis, as described in the associated research paper.