Experimental Data on Vitamin D3 and Calcium Effects on Kidney Stone Formation in Rats

An experimental dataset evaluating the effect of high-dose vitamin D3 and calcium supplementation on kidney stone formation in a rat model. The study was conducted by Maria Fátima de Paula Ramos and involved six treatment groups over a 30-day period. Results indicated a significant decrease in bladder stone formation and urinary calcium in groups receiving combined supplementation.

Use Cases

• Train models to predict treatment outcomes on kidney stone formation based on vitamin D3 and calcium dosage regimens described in the study.
• Analyze the relationship between urinary calcium levels and stone formation risk using the reported experimental group results.
• Compare the efficacy of different intervention groups (e.g., pellets + calcium vs. pellets + calcium + vitamin D3) for hypothesis testing in preclinical research.

Strengths

• The description provides specific, statistically significant results, including a 50% and 17% decrease in stone formation for two groups.
• The experimental design is clearly outlined with six distinct treatment groups and a 30-day administration period.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Last update date is unknown; freshness unverified.

Provenance

Source

Maria Fátima de Paula Ramos

Collection Method

Experimental model involving the insertion of pellets into the bladder of rats and administration of supplements.