Ibuprofen Release Profiles in Cellulose Acetate Membranes with Different Morphologies

An experimental dataset from a study evaluating the release profile of ibuprofen from cellulose acetate membranes with different morphologies. The work by Marcos V. Ferreira used drug release assays showing cumulative release curves over more than 50 hours for a symmetric membrane. Kinetic parameters were calculated from Higuchi and Korsmeyer/Peppas models, indicating diffusion/solution-controlled release.

Use Cases

• Modeling drug release kinetics based on membrane morphology described in the study.
• Comparing release profiles of symmetric versus asymmetric porous membranes for controlled delivery applications.
• Analyzing the effect of polymer matrix interactions on drug retention and release time.
• Benchmarking simulation models against experimental cumulative drug release curves.

Strengths

• Includes experimental results for drug release lasting over 50 hours for one membrane type.
• Compares multiple membrane morphologies (symmetric and asymmetric porous) with different release behaviors.
• Analysis uses established pharmacokinetic models (Higuchi and Korsmeyer/Peppas).

Limitations

• Row count and specific column-level documentation are unknown; field semantics must be inferred after download.
• Last update date is unknown; freshness unverified.
• Data scale is unclear, which may limit suitability assessment for large-scale modeling.

Provenance

Source

paperswithcode

Collection Method

Experimental laboratory study involving preparation of cellulose acetate membranes and drug release assays.