Nanoparticle Characterization and In Vivo Effects in Diabetic Rats

Ascorbic acid-functionalized zinc oxide nanoparticles with a homogeneous size of approximately 38 nm were synthesized and characterized. The dataset likely contains results from in vitro enzyme inhibition assays and in vivo tests on STZ-induced diabetic rats, including glycaemic control, lipid profiles, and cognitive performance metrics. Sindu M. B published this research on figshare in April 2026 under a CC-BY-4.0 license.

Use Cases

• Modeling dose-response relationships for nanoparticle efficacy based on in vitro enzyme inhibition data.
• Analyzing correlations between nanoparticle treatment and cognitive test performance (Morris water maze, open field tests) in diabetic animal models.
• Comparing the effects of different nanoparticle doses (25 and 50 mg/kg) on biochemical markers like lipid profiles and antioxidant enzyme levels.

Strengths

• Nanoparticles were characterized using multiple techniques (DLS, ZP, SEM, FTIR, XRD), suggesting detailed physicochemical data.
• In vivo results include statistically significant findings (p < 0.01, p < 0.001) from one-way/two-way ANOVA tests.
• The dataset is associated with a specific, peer-reviewed-sounding research study on a multifunctional nanomedicine technique.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for statistical modeling.
• The data is contained within PDF and DOCX files (7.5 MB total), which may require extraction and parsing.

Provenance

Source

figshare

Collection Method

Experimental research involving green synthesis, nanoparticle characterization, and animal model testing.

Freshness

Last updated 2026-04-28 10:59:35; freshness should be verified.