HA2 Peptide Orientation on Gold Nanoparticles in HeLa Cells (160 TEM Images)

160 transmission electron microscopy (TEM) images show the orientation of HA2-NNLACC peptides on gold nanoparticles incubated with HeLa cells. The dataset was created by Umbreen Shaheen and is associated with a scientific article. Full experimental details are available in the source publication.

Use Cases

• Analyze nanoparticle-peptide conjugate structure based on TEM images mentioned in the description
• Train computer vision models for nanoparticle detection and segmentation in cellular TEM images
• Study the cellular uptake and distribution of functionalized gold nanoparticles based on the experimental setup
• Validate computational models of peptide orientation on nanoparticle surfaces using the provided image data

Strengths

• Contains 160 TEM images, providing a visual dataset for analysis.
• Dataset is linked to a peer-reviewed scientific article for methodological context.
• Focuses on a specific, controlled experimental setup with 50% HA2-NNLACC and 50% CALNN peptides.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count and file format are unknown, which may limit suitability assessment.
• Data may reflect experimental bias inherent to the specific cell line and nanoparticle synthesis method.

Provenance

Source

Umbreen Shaheen via paperswithcode

Collection Method

Gold nanoparticles were capped with peptides and incubated with HeLa cells, followed by TEM imaging.