Notable iSNVs: Influenza A Virus Intra-Host Variants in Donor-Recipient Pairs

A figshare dataset by Hunter J. Ries, last updated in May 2026, cataloging intra-host single nucleotide variants (iSNVs) shared between donor and recipient samples. The 12.1 KB Excel file focuses on influenza A virus genes PB2, PB1, PA, HA, NP, and NA, excluding MP and NS genes due to overlapping reading frames.

Use Cases

• Identifying shared genetic variants between donor and recipient pairs based on the described iSNV data.
• Analyzing mutation patterns in specific influenza genes (PB2, PB1, PA, HA, NP, NA) mentioned in the description.
• Studying viral transmission bottlenecks by examining which iSNVs are conserved across infection events.
• Comparing genetic diversity across different influenza gene segments, excluding the MP and NS genes as noted.

Strengths

• Data is openly licensed under CC-BY-4.0, permitting broad reuse.
• Focuses on six key influenza A virus genes (PB2, PB1, PA, HA, NP, NA) as explicitly listed.
• Dataset is small (12.1 KB), facilitating quick download and initial inspection.

Limitations

• Row count is unknown, which may limit suitability assessment for statistical analysis.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality and completeness require manual inspection.

Provenance

Source

figshare, author Hunter J. Ries.

Collection Method

Likely derived from sequencing analysis of influenza A virus samples from donor-recipient pairs.

Time Range

The 'Merge_ID' column suggests data may be organized by year, but specific temporal coverage is not provided.

Freshness

Last updated 2026-05-07 17:42:30; freshness should be verified.

Geography

Geographic scope is not specified in the provided description.