Cytoplasmic Viscosity Measurements in Colorectal Cancer Cells via Nanoparticle Imaging

Fluorescence imaging data from genetically encoded nanoparticles used to measure cytoplasmic viscosity in colorectal cancer cell lines. The dataset likely contains diffusion coefficients and viscosity estimates derived from differential dynamic microscopy analysis. The data was uploaded by Steven Huysecom to figshare in April 2026.

Use Cases

• Compare cytoplasmic viscosity between cancer cell lines based on metastatic potential mentioned in the description
• Validate differential dynamic microscopy methods against single-particle tracking results described in the study
• Analyze nanoparticle diffusion coefficients in crowded cellular environments as referenced in the description

Strengths

• Dataset size is 109.5 MB, indicating substantial raw or processed imaging data
• Viscosity values for specific cell lines are provided (e.g., 1.9 to 2.3 cP for poorly metastatic, 3.6–3.7 cP for highly metastatic)
• Method validation against theoretical viscosities and single-particle tracking is described

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment

Provenance

Source

figshare

Collection Method

Data generated via differential dynamic microscopy of genetically encoded nanoparticles in colorectal cancer cell lines.

Freshness

Last updated 2026-04-10 06:04:40; freshness should be verified