Supplementary Material: MRI and CSF Biomarkers for 30 Amyloid-Positive Patients

30 patients with mild cognitive impairment or mild Alzheimer's disease were analyzed for a potential non-invasive imaging marker. The dataset includes TIF and XLSX files totaling 4.6 MB, published by figshare admin karger under a CC-BY-4.0 license. It was last updated on May 13, 2026.

Use Cases

• Correlating MRI-visible perivascular spaces with cerebrospinal fluid amyloid levels based on the described visual quantification.
• Investigating surrogate markers for vascular amyloid deposition based on the association between CSO-PVS burden and CSF Aβ40/Aβ42 levels.
• Comparing biomarker profiles between patient groups dichotomized by perivascular space burden based on the described median split method.

Strengths

• Includes data from 30 clinically characterized patients with mild cognitive impairment or mild Alzheimer's disease.
• Provides multi-modal data with both imaging (TIF) and tabular (XLSX) files.
• Published under a permissive CC-BY-4.0 license for open reuse.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The retrospective analysis of 30 patients suggests a relatively small sample size.

Provenance

Source

figshare admin karger

Collection Method

Retrospective analysis of patient data, with CSO-PVS visually quantified and dichotomized.

Freshness

Last updated 2026-05-13 05:56:01; freshness should be verified.