Zinc Oxide Nanoparticle Effects on Insulin Resistance in a Mouse Model

A 2026 study by Kanagavalli Ramasubbu investigates the therapeutic effects of zinc oxide nanoparticles on insulin resistance and neurodegeneration in a D-galactose-induced mouse model. The dataset likely contains results from bioinformatic and in vivo analyses, including blood glucose levels, amyloid-β deposition, and gene/protein expression data. It is shared under a CC-BY-4.0 license on figshare.

Use Cases

• Evaluating nanoparticle efficacy based on blood glucose and amyloid-β levels mentioned in the description
• Analyzing gene expression patterns for IRS/PI3K/AGER/APP signalling pathways described in the study
• Comparing therapeutic interventions using data from control, disease, and treatment groups
• Investigating correlations between oxidative stress markers and neurodegeneration outcomes

Strengths

• Includes data from a controlled in vivo study with five distinct treatment groups
• Measures multiple biological endpoints such as blood glucose, Amadori products, and gene expression

Limitations

• Dataset scale is limited to 18.7 KB, suggesting a small scope
• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment

Provenance

Source

figshare

Collection Method

In vivo analysis on C57BL/6 mice combined with bioinformatic analysis

Freshness

Last updated 2026-05-12 04:19:05