Toxicological Assessment of Au@Pt Nanorods in Mice via Intraperitoneal Injection

Aiyun Yang published a dataset on figshare in April 2026. It contains TIF images from a study evaluating the tissue distribution and toxicity of bimetallic Au@Pt nanorods in C57BL/6 mice over a 16-day period. The work assesses histopathology, hematology, and serum biochemical indicators following intraperitoneal administration.

Use Cases

• Analyze tissue distribution and accumulation patterns based on liver and spleen data mentioned in the description
• Model time-dependent biochemical changes based on catalase (CAT) and superoxide dismutase (SOD) activity indicators
• Assess histological safety for biomedical applications based on H&E staining results for inflammatory cell infiltration
• Correlate administration routes with toxicity profiles based on comparisons to intravenous injection studies mentioned

Strengths

• Data covers a 16-day observation period for time-dependent effects.
• Includes multiple assessment modalities: histopathology, hematology, and serum biochemistry.
• Dataset is openly licensed under CC-BY-4.0.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The 8.7 MB size indicates a relatively small dataset.

Provenance

Source

figshare

Collection Method

Experimental study on C57BL/6 mice, likely involving imaging and biochemical assays.

Time Range

Observation period of 16 days.

Freshness

Last updated 2026-04-11 10:20:03; freshness should be verified.

Geography

Laboratory study; geographic scope is not specified.