Two Cu(II) Coordination Polymers: Anti-Cancer Activity on Melanoma Cells

Zhaopeng Xuan prepared two new Cu(II)-containing coordination polymers using a mixed-ligand solvothermal approach. The dataset likely contains experimental results on the anti-cancer activity of these compounds against A375 melanoma cells. The data includes measurements from CCK-8, colony formation, and trans-well assays to assess cell viability, proliferation, migration, and invasion.

Use Cases

• Evaluating the anti-proliferative effects of coordination polymers based on CCK-8 assay results.
• Assessing the impact on cancer cell migration and invasion based on trans-well assay data.
• Comparing the biological activity of different coordination polymer structures described in the study.

Strengths

• Data is derived from specific, described experimental assays (CCK-8, colony formation, trans-well).
• Focuses on a defined cancer cell line (A375 melanoma cells) for consistent biological context.
• Compounds are precisely characterized with chemical formulas and synthesis conditions.

Limitations

• Row count and dataset scale are unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Last update date is unknown; freshness unverified.

Provenance

Source

Zhaopeng Xuan via paperswithcode

Collection Method

Experimental synthesis and biological assays (solvothermal synthesis, CCK-8, colony formation, trans-well).