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DNA/RNA sequences, gene expression, protein structures, metagenomics, single-cell sequencing
22,772 datasets
A 15.6 KB DOCX file contains a research article describing the antitumor mechanism of niraparib in BRCA wild-type ovarian cancer. The study, authored by Po-Wu Liu and published on figshare under CC-BY-4.0, investigates how niraparib promotes ferroptosis by inhibiting TM4SF1 expression via ALKBH1-mediated 6mA DNA modification. The document was last updated on June 1, 2026.
Single-cell and single-nuclear RNA sequencing data from paired carcinoma and para-carcinoma biopsy samples of 3 Lynch Syndrome patients, analyzed alongside public data from healthy controls and sporadic colorectal cancer patients. The dataset, authored by Junfeng Xu and shared under CC-BY-4.0, provides a transcriptomic resource for studying malignant transition. It was last updated on May 25, 2026.
Guofu Lin's research dataset underpins a study on lung adenocarcinoma (LUAD) progression. It includes multi-omics data from 517 tumor and 59 normal tissue samples from TCGA-LUAD, used to construct an 11-gene prognostic model. The dataset was last updated on 2026-05-25 and is shared under a CC-BY-4.0 license.
A collection of 151 Streptococcus agalactiae isolates from Brazil, sourced from semen, anovaginal, urine, and invasive clinical samples. The dataset provides epidemiological metadata and links to whole-genome sequence accession numbers in the European Nucleotide Archive and GenBank. It was authored by Ana clarisse merces and last updated on 2026-05-29.
Akhina Palollathil published a dataset on June 1, 2026, detailing phosphoproteomic analysis of the TRPM7 channel-kinase. The analysis integrates 569 phosphoproteomics profiling datasets and 116 differential abundance datasets. It identifies 55 Class I phosphosites in TRPM7, including 13 novel sites, and proposes potential upstream regulatory kinases.
A case report details two siblings diagnosed with COG5-related congenital disorder of glycosylation via whole genome sequencing. The 118.2 KB PDF, authored by Katherine Granger and licensed CC-BY-4.0, expands the known phenotypic spectrum of this rare metabolic disorder. It highlights the combination of optic atrophy, macular atrophy, and developmental delay not previously reported together.
Nine Quercus genome assemblies are integrated into the quercusTOA resource, which links protein-centric functional annotations with positional genomic data. The resource, created by Fernando Mora-Márquez and last updated in June 2026, provides a standardized framework for evolutionary studies across oak lineages. It includes a relational database and a user-friendly application for tasks like ortholog identification and phylogenetic tree construction.
Lingfeng Chen published R code for bioinformatics analysis on 2026-05-22. The code analyzes three Gene Expression Omnibus (GEO) datasets to identify key genes and pathways in acute pancreatitis-associated acute lung injury (AP-ALI). The 2.5 KB text file contains scripts for differential expression analysis, pathway enrichment, and protein-protein interaction network construction.
469 and 153 differentially expressed genes were identified from two mouse tissue datasets, with 94 overlapping genes. This dataset, created by Lingfeng Chen and last updated in May 2026, contains results from a cross-species bioinformatics analysis linking acute pancreatitis to acute lung injury. The analysis identified hub genes like IL-1β and CXCL2 and implicated the IL-17/NF-κB signaling pathway in the disease mechanism.
469 and 153 differentially expressed genes (DEGs) were screened from mouse lung tissue datasets GSE244335 and GSE216943, respectively, with 94 overlapping genes. The dataset, created by Lingfeng Chen and last updated on 2026-05-22, contains results from bioinformatic analyses including Gene Ontology, KEGG pathway, and protein-protein interaction network construction. It aims to identify key genes and shared pathogenic pathways associated with acute pancreatitis-associated acute lung injury.
2,920 ambulatory blood pressure monitoring (ABPM) records from 2,876 patients at the First Affiliated Hospital of Wannan Medical College, collected between December 2020 and March 2023. The dataset includes time-stamped systolic and diastolic blood pressure, heart rate, activity status, and posture readings, with binary labels for nocturnal systolic and diastolic hypertension. It was used to compare an ABPM-VAE model against a Fully Connected Neural Network (FCNN) for prediction tasks.
A 26.2 KB document details the genomic and phenotypic analysis of a fatal human bloodstream infection caused by Macrococcus caseolyticus subsp. caseolyticus in China. The data includes whole-genome sequencing results from the Illumina HiSeq platform and phenotypic tests for antimicrobial susceptibility and biofilm formation. The dataset was authored by Lifeng Shi and last updated on June 1, 2026.
A 2026 case report from China details the genomic and phenotypic analysis of a clinical bacterial isolate from a fatal human bloodstream infection. The dataset, authored by Lifeng Shi and shared under CC-BY-4.0, includes findings from whole-genome sequencing and antimicrobial susceptibility testing for the strain WH712. It is a small, single-case study with a file size of 26.2 KB.
A single clinical isolate, WH712, from a fatal human bloodstream infection caused by Macrococcus caseolyticus subsp. caseolyticus in China. The dataset includes whole-genome sequencing results and phenotypic testing data for antimicrobial susceptibility and biofilm-forming capacity. Author Lifeng Shi published the data under a CC-BY-4.0 license on figshare in 2026.
An Iranian endemic scorpion, Mesobuthus crucittii, provides the source for this venom gland transcriptome and bioactivity dataset. The data includes in silico analyses of a novel hyaluronidase sequence, molecular docking results, and experimental enzymatic assays. The dataset was authored by Masoumeh Baradaran and last updated on 2026-06-01.
A novel heterozygous missense variant (c.3916T > G, p.Y1306D) in the FBN2 gene was identified in a three-generation family with Congenital Contractural Arachnodactyly. The 724.2 KB PDF document, authored by Nan-Miao Wang and last updated in June 2026, details the clinical presentation and genetic analysis of this rare connective tissue disorder. This case report contributes to the known variant spectrum of FBN2, aiding in genetic counseling and molecular diagnostics for CCA.
A clinical case report describing a family with Congenital Contractural Arachnodactyly (CCA) across three generations. The report details the identification of a novel heterozygous missense variant in the FBN2 gene (c.3916T > G, p.Y1306D) via whole-exome sequencing. The dataset is a 423.7 KB PDF authored by Nan-Miao Wang and shared under a CC-BY-4.0 license.
A clinical case report and genomic analysis of a fatal human bloodstream infection caused by Macrococcus caseolyticus subsp. caseolyticus. The data includes whole-genome sequencing results, antimicrobial susceptibility testing, and biofilm-forming capacity for the clinical isolate WH712. The dataset was authored by Lifeng Shi and last updated on June 1, 2026.
One clinical isolate, strain WH712, from a fatal human bloodstream infection in China is described by genomic and phenotypic analyses. The data includes whole-genome sequencing results, antimicrobial susceptibility testing, and biofilm-forming capacity assays. The dataset was authored by Lifeng Shi and last updated on June 1, 2026.
Transcriptomic and bioactivity data from the venom gland of the Iranian endemic scorpion Mesobuthus crucittii, published by Masoumeh Baradaran in 2026. The dataset includes results from in silico analysis, molecular docking, and functional assays on a novel hyaluronidase enzyme. It is a small dataset (26.8 KB) shared under a CC-BY-4.0 license.